Tired All the Time
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Tired All the Time

If you wake up feeling drained, rely on caffeine just to get through the day, or find yourself crashing by mid-afternoon - you're not alone. Persistent fatigue can creep into every part of life, affecting your mood, focus, motivation, and even relationships. But tiredness isn’t always "just life" - it’s often a signal from your body that something’s out of balance. Our Tired All the Time blood test package is designed to uncover the root causes of your exhaustion, from nutrient deficiencies and thyroid issues to low iron or hidden inflammation. It’s a powerful first step in reclaiming your energy, clarity, and quality of life.

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38 BIOMARKERS

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Essential information about your test

What's in the test

What we measure:

  • Haemoglobin - Haemoglobin is the oxygen-carrying protein that gives red blood cells – and your blood – its rich red colour. This test checks how much haemoglobin is in your blood, giving a clear picture of how well oxygen is being transported throughout your body. It’s a key indicator of how efficiently your body is functioning.
  • Haematocrit (HCT) - measures the volume of your blood that’s made up of red blood cells.
  • Red blood cell (RBC) - This test measures the concentration of red blood cells (RBCs) in your bloodstream, which are essential for transporting oxygen from the lungs to tissues throughout the body and removing carbon dioxide for exhalation. An optimal RBC count is critical for supporting cellular energy, physical performance, and overall metabolic function.
  • MCV - Mean Corpuscular Volume indicates the average size of your red blood cells. This measurement provides insight into how effectively your red blood cells may be transporting oxygen throughout the body
  • MCH - Mean Corpuscular Haemoglobin reflects the average mass of haemoglobin within individual red blood cells
  • MCHC - Mean Corpuscular Haemoglobin Concentration represents the average concentration of haemoglobin within red blood cells.
  • RDW_ CV - Red Cell Distribution Width _ Coefficient of Variation quantifies the relative variation in red blood cell size by expressing it as a percentage. It provides an overview of how much red blood cell volume differs from the average size.
  • RDW_SD - Red Cell Distribution Width _ Standard Deviation measures the actual range between the smallest and largest red blood cells. Unlike RDW_CV, it is not influenced by the mean cell size and offers a direct assessment of red cell size diversity.
  • Platelets - Platelets are small, disc-shaped cell fragments produced in the bone marrow that play a key role in preventing blood loss. When a blood vessel is damaged, platelets rapidly activate, gather at the site, and help form a stable clot to seal the injury. This clotting process is essential for wound healing and maintaining vascular integrity.
  • MPV - Mean Platelet Volume reflects the average size of platelets circulating in the blood. As an indicator of platelet activity, MPV can offer insights into how actively the bone marrow is producing platelets.
  • P-LCR - Platelet Large Cell Ratio indicates the proportion of large platelets present in the blood, expressed as a percentage. It serves as a useful marker for assessing platelet turnover and function.
  • P-LCC - Platelet Large Cell Count measures the absolute number of large platelets in a given volume of blood. This value combines both platelet size and count, offering insight into the activity level of the platelet population.
  • PDW - Platelet Distribution Width assesses the variation in platelet size within a blood sample. It reflects how uniform or diverse the platelets are in terms of volume.
  • PCT - Plateletcrit represents the total volume of platelets in the blood, expressed as a percentage of the overall blood volume. It is calculated based on both the number and size of circulating platelets.
  • WCC - White Cell Count indicates the total number of white blood cells in your bloodstream. These cells are essential components of the immune system, working to detect, attack, and eliminate harmful pathogens such as bacteria, viruses, and other foreign substances. White cells also play a role in immune memory, helping your body respond more efficiently to repeated exposures.
  • Granulocyte count - Granulocytes are a category of white blood cells that include neutrophils, eosinophils, and basophils, all of which play vital roles in the body's first line of defence against infection. These cells contain granules filled with enzymes that help destroy bacteria, parasites, and other harmful organisms. The granulocyte count reflects the absolute number of these immune cells in the blood
  • Granulocyte percentage - Reflects the proportion of granulocytes relative to the total white blood cell count. This helps evaluate the distribution of immune cells and can offer important context when diagnosing infections, allergic reactions, or inflammatory conditions.
  • Lymphocytes count - Lymphocytes are specialised white blood cells that play a central role in the body’s adaptive immune response. They help recognise, target, and eliminate specific bacteria, viruses, and other pathogens. This group includes T cells, B cells, and natural killer (NK) cells, each with distinct immune functions. Lymphocytes also produce antibodies and memory cells, allowing the immune system to respond more rapidly to future exposures. An elevated or reduced lymphocyte count may indicate infection, immune system activity, or underlying haematological conditions
  • Lymphocyte Percentage - Reflects the proportion of lymphocytes in relation to the total white blood cell count. This value helps assess the balance of immune cell types.
  • MID - Mid-Sized Cell Count refers to the number of mid-sized white blood cells in circulation, primarily including monocytes, as well as eosinophils, and basophils. Unlike granulocytes, which act rapidly in acute immune responses, these mid-sized cells are involved in longer-term immune regulation, allergy response, and tissue repair. Monocytes, for example, help clear debris and develop into macrophages in tissues, while eosinophils and basophils play roles in managing allergic reactions and parasitic infections
  • MID Percentage - Mid-Sized Cell Count percentage shows the proportion of mid-sized white blood cells in relation to the total white blood cell count. This value helps assess how much of the immune system's activity is devoted to longer-term, regulatory responses rather than immediate infection control (typically handled by granulocytes).
  • Bilirubin - Bilirubin is a substance your body makes when it breaks down old red blood cells. It's processed by your liver and eventually leaves your body through urine and stool. If bilirubin levels build up, it can be a sign your liver isn’t clearing it properly, something that may cause yellowing of the skin or eyes. It’s also the reason bruises can look yellow as they heal.
  • ALP - Alkaline Phosphatase is an enzyme found in several parts of the body, including the liver, bones, and bile ducts. In liver health, it helps move substances through the bile ducts.
  • ALT - Alanine Aminotransferase is an enzyme mostly found in liver cells. When the liver is damaged or inflamed from things like fatty liver, hepatitis, or alcohol use ALT can leak into the bloodstream. That’s why it’s a key marker for spotting liver cell injury. Regular testing can help you catch liver stress early, even if you’re not feeling any symptoms.
  • AST - AST is an enzyme found in the liver but also in the heart, muscles, and other tissues. While it’s not as liver specific as ALT, it’s still an important part of assessing liver health. When liver cells are damaged, AST can rise, and when measured alongside other enzymes, it helps build a clearer picture of what might be affecting your liver.
  • GGT - GGT is a liver enzyme that plays a role in processing toxins and moving substances through the liver and bile ducts. It’s especially sensitive to alcohol use and certain medications.
  • Total Protein - Total protein gives an overall picture of the protein levels in your blood, made up mainly of two types - albumin and globulin. These proteins do all sorts of essential jobs: from carrying nutrients around your body to supporting your immune system. If your total protein levels are too high or too low, it could be a sign that something’s off with your nutrition, liver, or kidneys.
  • Albumin - Albumin is a protein made by your liver that helps keep everything in balance. It holds fluid inside your blood vessels, so it doesn’t leak into other parts of your body, and it also acts like a transport system - carrying things like vitamins, hormones, and even medications through your bloodstream. Healthy albumin levels are a good sign that your liver is working well and that your body is getting the nutrition/hormones it needs to heal, grow, and stay energised
  • Globulin - Globulins are a group of proteins in your blood that help with some of your body’s most important jobs. They support your immune system by fighting off infections, help move nutrients like iron around, and even play a role in keeping your blood healthy. Some globulins act as antibodies - your body’s natural defence system. Checking globulin levels can give insight into how well your immune system and liver are doing.
  • Creatinine - Creatinine is a waste product produced by muscles during everyday activity. It's released into the bloodstream and filtered out by the kidneys, making it a reliable indicator of how well your kidneys are functioning. Monitoring creatinine provides important insight into your body’s ability to clear waste effectively.
  • Urea - Urea is formed when your body processes protein, with the liver breaking it down into this waste product. It’s then carried through the bloodstream to the kidneys, which remove it and pass it out in urine. Checking urea levels in the blood can offer useful clues about how well your kidneys are clearing waste and how efficiently your liver is handling protein metabolism. However, because your body can often compensate with just one healthy kidney, results may appear normal even if some kidney function is impaired.
  • eGFR - Estimated glomerular filtration rate (eGFR) is a key measure of how efficiently your kidneys are filtering waste from your blood. It reflects the function of tiny filtering units in the kidneys called glomeruli. When these filters aren’t working properly, waste can build up in the body.
  • Thyroid stimulating hormones (TSH) – to see if your thyroid is slowing things down.
  • HbA1c - HbA1c (glycated haemoglobin) forms when glucose (sugar) in your blood attaches to haemoglobin in red blood cells. Because red blood cells live for about 3 months, measuring HbA1c gives an average of your blood sugar levels over that period. The higher your blood sugar, the more HbA1c you’ll have - making it a reliable marker for identifying long-term blood sugar control and diabetes risk.
  • Ferritin - Ferritin is the protein your body uses to store iron for future use. While iron is typically used to make haemoglobin - which carries oxygen in your blood - any extra is tucked away in ferritin, ready to be released when needed. Checking your ferritin levels provides a clear picture of your body’s iron reserves. It’s a valuable marker for understanding your overall iron status and energy levels.
  • Hs-CRP - C-reactive protein (CRP) is a substance your body produces in response to inflammation - a natural part of healing, but also a sign that something may be off. While regular CRP tests detect more obvious inflammation from injury or infection, the high-sensitivity CRP (hs-CRP) test is designed to pick up much smaller, subtler changes. These low levels of inflammation often don’t cause symptoms but can quietly affect your blood vessels over time, increasing the risk of heart disease or stroke
  • Vitamin D - Although it’s called a vitamin, vitamin D functions more like a hormone - made in the skin when exposed to sunlight. To be useful in the body, it must be converted into a form called 25-hydroxyvitamin D (25 OH), which is what this test measures. This is the most reliable way to assess how much vitamin D your body has available. Beyond supporting bone strength and calcium absorption, vitamin D also contributes to muscle performance, immune defence, mood stability, and even blood sugar regulation. Deficiency is especially common in the UK, particularly among those with darker skin or who spend limited time outdoors. Symptoms like low energy, muscle aches, weakened immunity, and mood changes may be signs your levels are too low. While foods like oily fish and fortified products offer small amounts, they're rarely enough to correct a deficiency - making testing a valuable first step toward better health.

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