Premier Cardiovascular & Metabolic Health Screen
Comprehensive Panel2–3 Day ResultsDoctor Consultation

Premier Cardiovascular & Metabolic Health Screen

The ultimate 360° health assessment - over 150 biomarkers for unmatched insight into your heart, hormones, and overall wellbeing. Our most advanced and exclusive blood test, this package is designed to provide a comprehensive overview of cardiovascular, metabolic, hormonal, and immune health. With over 150 biomarkers, it not only assesses cholesterol and apolipoproteins but also covers inflammation, glucose metabolism, kidney and liver health, thyroid balance, iron status, essential vitamins and minerals, and key male/female hormone panels.

4.9/5

£375

Heart HealthMetabolismWellbeing

150 BIOMARKERS

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Essential information about your test

What's in the test:

What we measure:

  • Haemoglobin - Haemoglobin is the oxygen-carrying protein that gives red blood cells – and your blood – its rich red colour. This test checks how much haemoglobin is in your blood, giving a clear picture of how well oxygen is being transported throughout your body. It’s a key indicator of how efficiently your body is functioning.
  • Haematocrit (HCT) - measures the volume of your blood that’s made up of red blood cells.
  • Red blood cell (RBC) - This test measures the concentration of red blood cells (RBCs) in your bloodstream, which are essential for transporting oxygen from the lungs to tissues throughout the body and removing carbon dioxide for exhalation. An optimal RBC count is critical for supporting cellular energy, physical performance, and overall metabolic function.
  • MCV - Mean Corpuscular Volume indicates the average size of your red blood cells. This measurement provides insight into how effectively your red blood cells may be transporting oxygen throughout the body
  • MCH - Mean Corpuscular Haemoglobin reflects the average mass of haemoglobin within individual red blood cells
  • MCHC - Mean Corpuscular Haemoglobin Concentration represents the average concentration of haemoglobin within red blood cells.
  • Platelets - Platelets are small, disc-shaped cell fragments produced in the bone marrow that play a key role in preventing blood loss. When a blood vessel is damaged, platelets rapidly activate, gather at the site, and help form a stable clot to seal the injury. This clotting process is essential for wound healing and maintaining vascular integrity.
  • MPV - Mean Platelet Volume reflects the average size of platelets circulating in the blood. As an indicator of platelet activity, MPV can offer insights into how actively the bone marrow is producing platelets.
  • WCC - White Cell Count indicates the total number of white blood cells in your bloodstream. These cells are essential components of the immune system, working to detect, attack, and eliminate harmful pathogens such as bacteria, viruses, and other foreign substances. White cells also play a role in immune memory, helping your body respond more efficiently to repeated exposures.
  • Lymphocytes count - Lymphocytes are specialised white blood cells that play a central role in the body’s adaptive immune response. They help recognise, target, and eliminate specific bacteria, viruses, and other pathogens. This group includes T cells, B cells, and natural killer (NK) cells, each with distinct immune functions. Lymphocytes also produce antibodies and memory cells, allowing the immune system to respond more rapidly to future exposures. An elevated or reduced lymphocyte count may indicate infection, immune system activity, or underlying haematological conditions
  • Basophil Count - Basophils are the least common type of white blood cell, but they play an important role in allergic reactions and inflammation. They release histamine and other chemicals that help the body respond to allergens, infections, and injury. Elevated basophils may be linked to allergic conditions, chronic inflammation, or certain blood disorders.
  • Lymphocyte Count - Lymphocytes are crucial defenders in your immune system, responsible for recognizing and fighting viruses, bacteria, and even abnormal or cancerous cells. They include B cells (which produce antibodies) and T cells (which directly attack infected cells or coordinate immune responses). Changes in lymphocyte levels may indicate infection, immune dysfunction, or blood-related conditions.
  • Eosinophil Count - Eosinophils help combat parasitic infections and are strongly involved in allergic reactions and asthma. They release enzymes and chemicals that regulate inflammation. Elevated eosinophils may be a sign of allergies, asthma, parasitic infections, or certain autoimmune conditions.
  • Monocyte Count - Monocytes are large white blood cells that circulate in the bloodstream before moving into tissues, where they become macrophages. Macrophages “eat” and break down bacteria, dead cells, and debris, making them vital for both defence and tissue repair. High monocyte levels may be seen in infections, inflammation, or immune-related disorders.
  • Neutrophil Count - Neutrophils are the most abundant type of white blood cell and your body’s first line of defence against bacterial infections. They respond rapidly to infection or injury, engulfing and destroying harmful microbes. A low count may increase the risk of infections, while a high count often signals an active infection or inflammation.
  • Creatinine - Creatinine is a waste product made by your muscles and filtered out of the blood by the kidneys. Measuring creatinine levels helps assess how well your kidneys are working, as a rise may signal reduced kidney function.
  • eGFR (Estimated Glomerular Filtration Rate) - eGFR is a calculation based on creatinine, age, sex, and other factors. It estimates how efficiently your kidneys are filtering waste from the blood, giving a clear picture of overall kidney function. Lower eGFR values may indicate early or advanced kidney disease.
  • Urea - Urea is another waste product created when your body breaks down protein. Healthy kidneys remove urea through urine. Elevated levels can suggest dehydration, high protein intake, or reduced kidney function.
  • Cystatin C - Cystatin C is a protein produced by all cells in the body and cleared by the kidneys. Unlike creatinine, it is less influenced by muscle mass, making it a sensitive and reliable marker of kidney health.
  • Sodium - Sodium is an essential electrolyte that helps control fluid balance, blood pressure, and nerve and muscle function. Abnormal levels may point to dehydration, kidney issues, or hormonal imbalances.
  • Potassium - Potassium is vital for heart rhythm, muscle contractions, and nerve signals. Both high and low potassium levels can be serious, sometimes causing muscle weakness, irregular heartbeat, or other complications.
  • Chloride - Chloride works with sodium and potassium to maintain fluid balance, acid–base balance, and proper nerve and muscle function. Changes in chloride can reflect dehydration, kidney disorders, or problems with acid–base regulation.
  • Phosphate - Phosphate supports energy production, bone strength, and cell function. It is tightly regulated by the kidneys, vitamin D, and hormones. Abnormal phosphate levels may be linked to bone disease, kidney problems, or hormonal changes.
  • Magnesium - Magnesium is needed for hundreds of biochemical reactions, including energy production, muscle function, and nerve transmission. Low or high levels may cause fatigue, cramps, irregular heartbeat, or neurological symptoms.
  • Calcium (Adjusted) - Calcium is essential for healthy bones, teeth, nerves, and muscles. “Adjusted calcium” accounts for protein levels in the blood (mainly albumin), giving a more accurate measure of the calcium available to the body. Abnormal levels can signal bone disease, vitamin D problems, or parathyroid hormone imbalances.
  • Alkaline Phosphatase (ALP) - ALP is an enzyme found in the liver, bones, and digestive tract. High levels may indicate liver disease, bile duct problems, or increased bone activity.
  • Alanine Aminotransferase (ALT) - ALT is an enzyme mainly found in the liver. Raised ALT often signals liver irritation or damage, such as from fatty liver, alcohol, or viral hepatitis.
  • Aspartate Aminotransferase (AST) - AST is another enzyme involved in liver and muscle function. High levels may indicate liver stress, muscle injury, or heart conditions when combined with other findings.
  • Gamma-Glutamyl Transferase (GGT) - GGT is an enzyme linked to bile ducts and alcohol metabolism. Elevated GGT can be an early sign of liver or bile duct problems and is often raised with heavy alcohol use.
  • Total Bilirubin - Bilirubin is a yellow pigment made when red blood cells break down. The liver processes and removes it. High bilirubin may cause jaundice and indicate liver or bile duct problems.
  • Albumin - Albumin is a protein made by the liver that helps maintain fluid balance and transport nutrients and hormones. Low levels may suggest liver disease, kidney problems, or malnutrition.
  • Iron - Iron is an essential mineral that your body uses to make haemoglobin — the protein in red blood cells that carries oxygen around the body. Low iron can cause anaemia and fatigue, while high levels may indicate overload conditions.
  • Ferritin - Ferritin is a protein that stores iron in your body. Measuring ferritin shows how much iron you have in reserve. Low levels suggest iron deficiency, while high levels may indicate inflammation or iron overload.
  • Transferrin - Transferrin is a protein that carries iron through the blood to where it’s needed. Measuring transferrin helps assess how well your body is transporting and regulating iron.
  • Transferrin Saturation - These measures how much of the transferrin in your blood is loaded with iron. It provides insight into whether your body has enough available iron for healthy red blood cell production.
  • Total Iron Binding Capacity (TIBC) - TIBC reflects the total amount of iron that your blood proteins (mainly transferrin) can carry. It is often higher when iron stores are low, making it useful for diagnosing iron deficiency.
  • Vitamin D - Vitamin D is vital for healthy bones, muscles, and immune function. It helps your body absorb calcium and phosphate. Low levels are common, especially in winter, and can cause fatigue, weak bones, low mood, or increased risk of infections.
  • Folic Acid (Vitamin B9) - Folic acid is a B vitamin needed to make red blood cells and DNA. It plays a key role in energy production and cell growth. Low levels may cause anaemia, fatigue, or, in pregnancy, increase the risk of developmental problems.
  • Vitamin B12 - Vitamin B12 is essential for healthy nerves, red blood cell production, and energy metabolism. Deficiency can lead to tiredness, numbness, tingling, memory issues, or anaemia. It is more common in people with restricted diets (such as vegan), gut absorption issues, or autoimmune conditions.
  • Total Antioxidant Status (TAS) – This test measures the overall ability of your blood to counteract harmful molecules called free radicals. Free radicals can damage cells and contribute to ageing, inflammation, and chronic diseases such as heart disease and cancer. A healthy antioxidant status suggests your body has enough protection from diet and natural defences, while low levels may reflect poor nutrition, high oxidative stress, or certain health conditions
  • Thyroid Stimulating Hormone (TSH) - TSH is made by the pituitary gland and controls how much hormone your thyroid produces. High levels usually suggest an underactive thyroid (hypothyroidism), while low levels may point to an overactive thyroid (hyperthyroidism).
  • Free Thyroxine (fT4) - Free T4 is the main hormone released by the thyroid gland. It helps regulate metabolism, energy, and body temperature. Measuring fT4 alongside TSH shows whether your thyroid is working normally or if it’s under- or overactive.
  • Free Triiodothyronine (fT3) - Free T3 is the active thyroid hormone that drives many of the body’s metabolic processes. It is especially useful in assessing suspected overactive thyroid, as it can be raised even when fT4 appears normal.
  • Anti-Thyroglobulin Antibodies (Anti-Tg) - These antibodies target thyroglobulin, a protein made by the thyroid gland. Their presence may indicate autoimmune thyroid conditions such as Hashimoto’s thyroiditis or, less commonly, Graves’ disease.
  • Anti-Thyroid Peroxidase (TPO) Antibodies - TPO antibodies attack thyroid peroxidase, an enzyme essential for thyroid hormone production. High levels are commonly seen in autoimmune thyroid disease, particularly Hashimoto’s and Graves’ disease, and can help explain long-term thyroid dysfunction.
  • Glucose (Random) - Glucose is the main type of sugar in your blood and your body’s primary energy source. Measuring glucose gives a snapshot of your current blood sugar level, which can help detect diabetes or prediabetes.
  • HbA1c (3-month blood sugar control) - HbA1c reflects your average blood sugar levels over the past 2–3 months. Unlike a single glucose reading, it shows long-term blood sugar control and is a reliable marker for diagnosing and monitoring diabetes.
  • Insulin - Insulin is the hormone that helps move glucose from the bloodstream into your cells for energy. Measuring insulin levels can show how well your body is handling sugar and whether insulin resistance (a key feature of type 2 diabetes) may be present.
  • C-Peptide - C-Peptide is released in equal amounts to insulin when your body makes its own insulin. Measuring it helps distinguish between type 1 and type 2 diabetes and shows whether your pancreas is still producing insulin effectively.
  • Oestradiol (E2) - Oestradiol is the main form of oestrogen in women. It plays a central role in regulating the menstrual cycle, ovulation, and uterine lining. Abnormal levels may affect fertility and menstrual regularity.
  • Follicle Stimulating Hormone (FSH) - FSH helps control the menstrual cycle and stimulates the growth of eggs in women and sperm production in men. High levels may suggest reduced ovarian reserve in women or testicular issues in men.
  • Luteinising Hormone (LH) - LH triggers ovulation in women and supports testosterone production in men. Abnormal LH levels can point to ovulation problems, polycystic ovary syndrome (PCOS), or pituitary dysfunction.
  • Progesterone - Produced after ovulation, progesterone prepares the uterus for pregnancy. Low levels may indicate that ovulation isn’t occurring regularly, which can affect fertility.
  • Prolactin - Prolactin is primarily involved in milk production after childbirth, but raised levels outside of pregnancy can disrupt ovulation and fertility.
  • Testosterone - Although typically thought of as a male hormone, testosterone is also important in women for libido, mood, and ovarian function. Abnormal levels in women may suggest PCOS, while in men it reflects testicular and reproductive health.
  • Sex Hormone Binding Globulin (SHBG) - SHBG is a protein that binds sex hormones like testosterone and oestradiol. Measuring it helps determine how much “free” (active) hormone is available.
  • Free Androgen Index (FAI) - FAI is a calculation based on testosterone and SHBG. It helps identify whether androgen (male hormone) levels are in balance, particularly important in women with suspected PCOS
  • Total PSA – Prostate-Specific Antigen (PSA) is a protein made by the prostate gland. Small amounts naturally circulate in the blood, but higher levels can suggest changes in prostate health. Elevated PSA may be linked to prostate enlargement (benign prostatic hyperplasia), inflammation (prostatitis), or prostate cancer. Because many factors can influence PSA, results are best interpreted alongside age, symptoms, and medical history.
  • CA-125 – Cancer Antigen 125 (CA-125) is a protein that can be found in the blood. It is often used as a marker for ovarian health. Higher levels may be seen in ovarian cancer, but they can also rise with non-cancerous conditions such as endometriosis, menstruation, pelvic infections, or liver disease. Because of this, CA-125 is not used alone for diagnosis but can help monitor ovarian conditions or treatment response.
  • Uric Acid – Uric acid is a natural waste product formed when the body breaks down purines, substances found in certain foods and in your cells. Normally, uric acid is filtered out by the kidneys and passed in urine. Elevated levels may lead to crystal buildup in the joints, causing gout, and can also be linked to kidney stones or reduced kidney function. Low levels are less common but may occur with some medical conditions or medications.
  • Creatine Kinase (CK) – Creatine kinase is an enzyme found mainly in the heart, brain, and skeletal muscles. It is released into the blood when muscle tissue is damaged. Elevated levels can indicate muscle injury, intense exercise, heart attack, or certain muscle diseases.
  • Rheumatoid Factor (RF) – Rheumatoid factor is an antibody sometimes produced by the immune system. Higher levels are often associated with autoimmune conditions such as rheumatoid arthritis, but they can also be raised in other inflammatory or infectious diseases. A positive result does not confirm arthritis on its own but may guide further investigation.
  • Leptin – Leptin is a hormone produced by fat cells that helps regulate appetite and body weight. It signals to the brain when you’ve had enough to eat. Higher levels can be seen with obesity and may indicate “leptin resistance,” where the body no longer responds properly to the hormone. Very low levels are rare but may affect energy balance and fertility.
  • Adiponectin – Adiponectin is a hormone released by fat tissue that plays a key role in regulating blood sugar and fatty acid breakdown. Higher levels are generally protective, linked to lower risk of heart disease and diabetes. Low levels are often found in people with obesity, insulin resistance, or cardiovascular disease.
  • Resistin – Resistin is another hormone produced by fat cells and immune cells. It has been linked to inflammation and may play a role in insulin resistance, type 2 diabetes, and cardiovascular disease. Higher levels are often associated with obesity and chronic inflammation.
  • Total Cholesterol - Total cholesterol is the overall amount of cholesterol in your blood. While your body needs cholesterol for hormones, cells, and digestion, too much can raise your risk of heart disease and stroke.
  • LDL Cholesterol (“bad” cholesterol) - LDL carries cholesterol to the arteries. High levels can cause fatty deposits (plaques) to build up, narrowing the arteries and increasing the risk of heart attack and stroke.
  • HDL Cholesterol (“good” cholesterol) - HDL helps remove excess cholesterol from the blood, transporting it back to the liver for processing. Higher HDL is protective against heart disease.
  • Total Cholesterol / HDL Ratio - This ratio compares overall cholesterol to protective HDL. A lower ratio generally means a healthier balance and a lower risk of cardiovascular problems.
  • Triglycerides - Triglycerides are a type of fat in the blood, stored for energy. High levels can increase the risk of heart disease and are often linked to diet, obesity, diabetes, or excessive alcohol intake.
  • Apolipoprotein A-I (ApoA-I) – ApoA-I is the main protein in HDL cholesterol (“good cholesterol”). It helps remove excess cholesterol from the bloodstream and transport it to the liver for disposal. Higher levels are generally linked to a lower risk of heart disease.
  • Apolipoprotein B (ApoB) – ApoB is the main protein found in LDL cholesterol and other “bad” cholesterol particles. It represents the number of cholesterol-carrying particles that can contribute to plaque build-up in arteries. Higher levels are strongly linked to cardiovascular risk.
  • Apolipoprotein B / A-I Ratio – This ratio compares the amount of “bad” ApoB particles to “good” ApoA-I particles. A higher ratio indicates greater risk of atherosclerosis (narrowing of arteries), while a lower ratio suggests a healthier balance.
  • Apolipoprotein C-II (ApoC-II) – ApoC-II helps activate enzymes that break down triglycerides in the blood. Abnormal levels may contribute to high triglycerides and increased cardiovascular risk.
  • Apolipoprotein C-III (ApoC-III) – ApoC-III slows down the removal of triglycerides from the bloodstream. Higher levels are associated with raised triglycerides and greater risk of heart disease and diabetes.
  • Apolipoprotein E (ApoE) – ApoE plays a key role in how the body processes cholesterol and fats. Different genetic forms of ApoE can affect risk of heart disease and, in some cases, Alzheimer’s disease.
  • Lipoprotein (a) [Lp(a)] – Lp(a) is a type of cholesterol particle that is mostly inherited. High levels increase the risk of heart attack and stroke, even when other cholesterol results are normal.
  • Cardiovascular Risk Score – This score combines several biomarkers (such as cholesterol levels, inflammation markers, and other risk factors) to estimate your likelihood of developing heart disease. It provides a clearer picture of overall cardiovascular risk.
  • Parathyroid Hormone (PTH) – PTH is a hormone made by the parathyroid glands in the neck. It helps regulate calcium, phosphate, and vitamin D levels in the body, which are vital for healthy bones, muscles, and nerves. High levels may suggest parathyroid gland overactivity or low vitamin D, while low levels can be linked to underactive parathyroid glands or certain medical treatments.
  • Complement Component 3 (C3) – C3 is part of the immune system’s complement pathway, which helps fight infection. Abnormal levels may be linked to autoimmune conditions, infections, or kidney disease.
  • Complement Component 4 (C4) – Like C3, C4 is an immune system protein. Low levels may indicate autoimmune conditions such as lupus, while high levels may reflect ongoing inflammation.
  • Immunoglobulin A (IgA) – IgA is an antibody mainly found in the mucous membranes (respiratory and digestive tracts). Abnormal levels may indicate infections, immune deficiencies, or autoimmune conditions.
  • Immunoglobulin G (IgG) – IgG is the most common antibody in the blood, providing long-term protection after infection or vaccination. Low levels may suggest immune deficiency, while high levels may reflect chronic infection or autoimmune disease.
  • Immunoglobulin M (IgM) – IgM is the first antibody the body makes when fighting a new infection. High levels suggest recent or ongoing infection, while low levels may point to immune system problems.
  • Anti-streptolysin O (ASO) – ASO antibodies develop after infection with group A streptococcus bacteria. High levels may suggest a recent strep throat or related infection and can help identify post-streptococcal complications, such as rheumatic fever.
  • C-Reactive Protein (CRP) - CRP is a protein made by the liver in response to inflammation. Levels rise when there is infection, injury, or chronic inflammatory activity in the body. Measuring CRP helps detect hidden inflammation and can support the investigation of conditions such as infections, autoimmune disease, or cardiovascular risk.
  • Pancreatic Amylase – Amylase is an enzyme made by the pancreas (and salivary glands) that helps break down carbohydrates. High levels in the blood may suggest pancreatitis (inflammation of the pancreas), pancreatic obstruction, or other digestive issues. Low levels may occur with chronic pancreatic disease.
  • Lipase – Lipase is another enzyme produced by the pancreas, responsible for breaking down fats. Like amylase, high levels often point to pancreatitis or other pancreatic disorders, while low levels may suggest long-term pancreatic damage.
  • H. Pylori – Helicobacter pylori is a type of bacteria that can infect the stomach lining. It is a common cause of stomach ulcers and can increase the risk of gastritis and, in some cases, stomach cancer. A positive result means further treatment may be needed to clear the infection.
  • Anti-Tissue Transglutaminase Antibodies (tTG-IgA/IgG) – These antibodies are often measured to screen for coeliac disease, an autoimmune condition where the immune system reacts to gluten (a protein in wheat, barley, and rye). High levels suggest that the immune system is attacking the small intestine in response to gluten.
  • Immunoglobulin E (IgE) – IgE is an antibody made by the immune system in response to allergens. High levels may suggest allergies (such as hay fever, asthma, eczema, or food allergies) or, in some cases, parasitic infections.

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